Abode Reader X Save Icon is grayed out.

I have a Lenovo x220 running Windows 7 and when I open a pdf in Adobe Reader X, it won't let me just "save". I can "save as" but I can not just save. The icon for saving is also grayed out. When I hit Ctrl + S, nothing happens. It will save under "save as" just fine though.

What I've been doing is using the keyboard command Ctrl+Shift+S, which brings up the Save As... dialog box.
Like thinksink, I receive PDFs by email. I scan documents using our printer/scanner/fax machine, and it sends the documents to my email account as PDF files. By default, the documents are named "scan.pdf", and it is inconvenient to type in a different document title before sending. So, when scan.pdf arrives in my inbox, I open the file to ensure that the document has scanned correctly, and if it has, I save it to the appropriate folder on my drive.
In Reader 9, I could click the Save... button (which was NOT greyed out), and the Save As... dialog box would open. I think the first time I did that, I was shown a warning that changes to the document could not be saved and if I wanted to save it, I would have to save it to a file with a different name. Since this is exactly what I intended to do, everything worked great. And, I didn't have to see the warning every time because there was a "Don't show me this again" check box.
Another related annoying change from Reader 9 is that Reader X doesn't remember what folder I saved the last document to. In the Save As... dialog box, the saving process for each document always starts in the temporary folder that Outlook stores attachments in, and I have to work my way through the directory tree to save each file. This occurs even when I leave the application running and just close the last document.

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Why do I have to File Save twice before the Save menu is grayed out?

Open a file into Photoshop CC
Add a Levels layer
Click File>Save
The Save menu is still available when you click File. Doing another File>Save make the Save menu become grayed out (like it should the first time).
System info:
Adobe Photoshop Version: 2014.2.1 20141014.r.257 2014/10/14:23:59:59 CL 987299 x64
Operating System: Mac OS 10.10.1 (the problem has occurred since Mac OS 10.8.x)
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Daniel

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So I will open a PSD with an adjustment layer.
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Hi,
the "Save" Button is greyed out with every PDF File.
File -> Save is also grey
File -> Save as... is functional.
Where's the Problem?

What I've been doing is using the keyboard command Ctrl+Shift+S, which brings up the Save As... dialog box.
Like thinksink, I receive PDFs by email. I scan documents using our printer/scanner/fax machine, and it sends the documents to my email account as PDF files. By default, the documents are named "scan.pdf", and it is inconvenient to type in a different document title before sending. So, when scan.pdf arrives in my inbox, I open the file to ensure that the document has scanned correctly, and if it has, I save it to the appropriate folder on my drive.
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Abode Reader X Save Icon is grayed out.

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