Adobe Bridge crashes

Question

Adobe Bridge crashes with this event and locks up my computer.  How can I fix this?
Log Name:      Application
Source:        Microsoft-Windows-User Profiles Service
Date:          6/29/2013 12:03:51 PM
Event ID:      1530
Task Category: None
Level:         Warning
Keywords:     
User:          SYSTEM
Computer:      Tachyon
Description:
Windows detected your registry file is still in use by other applications or services. The file will be unloaded now. The applications or services that hold your registry file may not function properly afterwards. 
DETAIL -
2 user registry handles leaked from \Registry\User\S-1-5-21-3178567393-178064881-3290291851-1000_Classes:
Process 4764 (\Device\HarddiskVolume2\Program Files\Adobe\Adobe Bridge CS6 (64 Bit)\Bridge.exe) has opened key \REGISTRY\USER\S-1-5-21-3178567393-178064881-3290291851-1000_CLASSES
Process 4764 (\Device\HarddiskVolume2\Program Files\Adobe\Adobe Bridge CS6 (64 Bit)\Bridge.exe) has opened key \REGISTRY\USER\S-1-5-21-3178567393-178064881-3290291851-1000_CLASSES
Event Xml:
<Event xmlns="http://schemas.microsoft.com/win/2004/08/events/event">
  <System>
    <Provider Name="Microsoft-Windows-User Profiles Service" Guid="{89B1E9F0-5AFF-44A6-9B44-0A07A7CE5845}" />
    <EventID>1530</EventID>
    <Version>0</Version>
    <Level>3</Level>
    <Task>0</Task>
    <Opcode>0</Opcode>
    <Keywords>0x8000000000000000</Keywords>
    <TimeCreated SystemTime="2013-06-29T19:03:51.309111900Z" />
    <EventRecordID>9745</EventRecordID>
    <Correlation />
    <Execution ProcessID="1324" ThreadID="3120" />
    <Channel>Application</Channel>
    <Computer>Tachyon</Computer>
    <Security UserID="S-1-5-18" />
  </System>
  <EventData Name="EVENT_HIVE_LEAK">
    <Data Name="Detail">2 user registry handles leaked from \Registry\User\S-1-5-21-3178567393-178064881-3290291851-1000_Classes:
Process 4764 (\Device\HarddiskVolume2\Program Files\Adobe\Adobe Bridge CS6 (64 Bit)\Bridge.exe) has opened key \REGISTRY\USER\S-1-5-21-3178567393-178064881-3290291851-1000_CLASSES
Process 4764 (\Device\HarddiskVolume2\Program Files\Adobe\Adobe Bridge CS6 (64 Bit)\Bridge.exe) has opened key \REGISTRY\USER\S-1-5-21-3178567393-178064881-3290291851-1000_CLASSES
</Data>
  </EventData>
</Event>

Answer 1

Looks like some tool on your system is trying to rewrite registry keys while Bridge accesses them. Beyond that nobody can say anything. this will require major investigation using tools like Sysinternals' System Monitor...
Mylenium