All of a sudden my computer won't recognize my iphone, itunes won't open up at all, all of a sudden my computer won't recognize my iphone, itunes won't open up at all

Itunes won't open when I plug in my phone.  click on desktop icon, nothing.   tried unistall and install, still nothing.   i got  message"connection with server was reset.  Coulnd't install.  Help!

Troubleshooting depends on what computer OS you are using.
Since you do not indicate what you use, here are both.
Windows:  http://support.apple.com/kb/TS1538
OS X:  http://support.apple.com/kb/TS1591

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