Apps will not launch on my MacBook  OSX 10.4.6

I will download the .dmg file. Open it, and then copy to the Applications folder. Then when I click the fancy little icon for to launch the app, it goes to the dock for a second, then disappears and nothing happens.
please help

just standard apps
macamp and xchat to name a few
but, last night I re-installed OS X and that did the trick... everything is in working order now

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