Can not upgrade to desktop manager 5.0 in Vista

Frustrated- trying to delete 4.7 (not working) and do fresh install of 5.0  -  get registry error when uninstall tries to delete certain obscure entries
with 1405 error code - do not have permission to delete key etc.  - I am running as administrator - I have tried  regedit to check permissions and change etc. but there are too many entries - I searched for solutions and have tried everything including Microsofts enhanced remove program (Windows Install Clean Up) 
Thanks for any help!
Jay 

 By using the Windows Install Cleanup Utility, you are removing all the registry keys.
Can you install 5.0 on top of 4.7? You should be able to do this.
If I helped you please give me Kudos!!

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