Can't open PDFs from mail or saved to desktop.

I can't open any pdf file from mail. This is the error message I get..."The application “Adobe Reader” failed to open the attachment “HRA-Reg-SC-2009.pdf”. Would you like to save the file to disk?"
Then it says it "you cannot open this application because it is not supported on this architecture. Can anyone help me? Here I get a new computer and can't open pdfs

Could be an adobe issue. Is it up to date? Within Adobe in the Help menu, try repair adobe installation. In the mean time, right click on any pdf and Get Info. Under open with, change it to preview.
RM

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