Cannot open MS Office files directly from network

Hi all,
I'm having trouble opening Microsoft Office files off of a network drive. 
When opened, the application jumps straight into the template page (attached screenshot).
I can copy files onto my local machine and open them no problem, however if I have an existing file open (from the local machine) and subsequently try to open a network file, the local file is closed and the template page replaces it. 
The same symptoms occur when attempting a "Save As" to the network.
This topic first appeared in the Spiceworks Community

I've tried replacing the office plugin file NPOFF12.DLL from a working system to the bad system, and it didnt help. I got that by doing typing about:plugins in the address bar. This person can open PDF documents, it's just Office files that dont open. I get no prompt to do anything. I have seen threads about headers on the webpages, but I'm not sure if its applicable. I tried from OWA and it does the same thing; nothing.

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