Cannot save any changes - Microsoft Forefront 2010 for exchange is unable to perform the requested function

HI, I have Forefront 2010 for Exchange installed for an Exchange 2007 SP2 running on Windows 2003 x64 SP2. Exchange has all roles installed on the same server. 
When I try to save any change on Forefront I got the following message:
Microsoft Forefront 2010 for Exchange is unable to perform the requested function. This may be because Forefront services are unavailable. Ensure that all Microsoft Forefront services are running and that WindowsPower Shell is functional
Well, our FF services are running and PowerShell is functional. I checked some forums and found some problems when there is entries in the IP Allow / Block lists in Exchange UI. I removed those entries but problem remains.
Any ideas would be appreciated.
Xavier Villafuerte

In my case, I was able to work around this issue by using  PowerShell directly.  For example, to run an on-demand scan for all mailboxes, this worked:
#open EMS
$aliases = (get-mailbox -result unlimited).alias
Add-PsSnapin FSSPSSnapin
set-FseOnDemandScan -MailboxList $aliases
Start-FseOnDemandScan -EnableVirusScan $true
Windows 2008 R2 SP1
Exchange 2010 SP3, RU9
PowerShell 4.0 present on the machine (though EMS runs PS 2.0)
Forefront PowerShell cmdlets:
https://technet.microsoft.com/en-us/library/cc482986.aspx
Mike Crowley | MVP
My Blog --
Baseline Technologies

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