Error (-50) when trying to sync iPhone 5. Everything is up to date but I can not sync! HELP!!!!

So I try to sync my iPhone 5 to my MacBook Pro.   I store my iTune library on my external drive to save space.    I have been getting Error (-50). HELP!!!!

Hello, gdesign14.  
Thank you for visiting Apple Support Communities.  
I understand that you are receiving an error 50 when attempting to sync your iPhone.  Try restarting your iPhone, iTunes and then attempt the sync again.  
Restart or reset your iPhone, iPad, or iPod touch
If the issue persists, try the troubleshooting steps in the article below.  
iTunes: Resolve USB-related alerts
-Jason H.  

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