File Sender and Mail Receiver .....what is the error all about?

Dear All,
  I am trying to send a file using mailpackage to my Lotus Notes id.But it is giving the below mentioned error.
<b>error occured: [2005-09-28T11:42:43Z] unable to call the mailer; com.sap.aii.messaging.srt.BubbleException: Failed to call the endpoint [null "null"]; nested exception caused by: java.net.ConnectException: Connection refused: connect</b>
The below mentioned is my Input File.
<b><?xml version="1.0" encoding="UTF-8"?>
<ns:Mail xmlns:ns="http://sap.com/xi/XI/Mail/30">
   <Subject>Interesting</Subject>
   <From>MailMsg</From>
   <To>[email protected]</To>
   <X_Mailer>Lotus Notes</X_Mailer>
  <Content>Hi ra.</Content>
</ns:Mail></b>
and my Mail Adapter Configuration for this is,
<b>Transport Protocol: SMTP
Message Protocol: XIPAYLOAD
Adapter Engine: Integration Engine
URL: smtp://mailservername
User:
Password:
Use Mail Package is checked and
Encoding : None</b>
1.Should I have to have an access to the Mail Server?
2.Why is the error?
3.What all Configuration I need to change,if any?
4.How to solve the error?
Without running the scenario,when I went to Monitor ,it was showing,
<b>MyConfig. Scenario:MyMailAdapter as running:started</b>
Please help me to solve this problem.
Thank You

No Stefan,
  I don't have SP10.
Do I need make any new configuration on the Mail Server side or i can carry on with the existing corporate one (which I am not supposed to touch)?
I haven't created any mail server of my own.But I want to send that file to my corporate domain or my <b>yahoo</b> domain for example.Now should I need to make any new configuration or configuration changes on my Integration Server?
I am very much confused in this regard.I have not made any other configuration other than that of Mail Adapter and File Adapter(ie,only XI related configurations).
I didn't even configured my own smtp server.
This is what I have done so far.Can you please through more light on it?
Thanks in Advance,
  Sugata Basu

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