Garageband 3.01 will not load with System 10.4.4,5 or 6

Hello Helpful Forum
I upgraded to system 10.4.4 (then .5 and .6) on my 17in POWERBOOK 1.67. What a mistake. Not only does Garageband 3.0 or 3.0.1 not load but the Help feature in every program crashes whenver I try to use it. The BACKUP application for my .mac account also just spins the beachball and quits. I have repaired permissions, rebooted in SAFE mode, tunrned off Log-in items: all to no avail. Any suggestions as to why this systme upgrade screws up several APPLE applications?
Thanks in advance
Paul
1.67 Ghz G4 PowerBook   Mac OS X (10.4.6)  

Thanks for your suggesitons. Unfortunately none of them solved the problem so I went back to the starting line and reinstalled the original system 10.4 then upgraded to 10.3.9 and then reinstalled Garageband from iLife 06. The application opened. Unfortunately some websites on Safari do not open as usual so it is another round of troubleshooting. Tiger has bitten me once too often. sigh
Paul
Hi Paul,
i would suggest using single user mode.
Restart your computer. When the screen goes black,
hold down the "apple" key and the "S" key until you
get a black screen with white letters. When the
prompt shows up, type this exactly:
/sbin/fsck -fy
Notice the space before the -fy.
If this doesn't work, you should boot from your
system install CD/DVD or most recent OS install
CD/DVD and run Disk Utility to repair the disk and
repair the permissions.
Good luck and let us know how it works.
-xs4is

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