How to minimise side effects of any note / Patch Application

How can one know that what effect a note / Patch is going to have and what all transaction codes it will hit..
For example i applied one note which seems to have activated a certain schema which was earlier commented out in the system. resulting in the printing of payslip with incorrect details.
How can one minimize any side effects of any note applied in the system...kindly suggest.
Regards,
Ankush

Dear All,
The reason i ask this question on this forum is the fact that in the past few instances i have faced certain issues due to application of notes related to form 24Q (these are the oly notes we have applied)
and the issues are coming in Payroll, in payslips and certain areas which i feel should remain unaffected by the note application...
However i appreciate all he answers and also would like to urge SAP to maybe release atleast the standard Testing that should be done after a particular Note application. i do not know if this is a reasonable demand but it is always better to have it right from the horses mouth...
Hope you agree to this........and will garner support for the same......
Regards
Ankush

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