I have just upgraded my Ipad to IOS 5 and I am unable to use my applications

I have just upgraded my Ipad to IOS 5 and I am unable to use my applications.
The applications appear in the screen, but when I tap on any one of them, they do not open.
Can some one tell me what to do to be able to use my application again?

Sorry, I'm reposting this because of spelling error in my previous post (I must turn that 'auto-correct' off).
Since I posted my questions, the only thing I figured out was to turn the 'iCloud' in the Settings on and now the plus sign is on and all my previous appointments appeared.  While this is a solution, what if I don't want to use iCloud? But I'm happy for now that my Calendar works.

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