Issue with wired mouse

Question

I recently upgraded my mid-2011 iMac from Lion to Mountain Lion (10.8.2).  I am now having trouble with my wired mouse.  I use a two-button Microsoft mouse which worked fine for a year with Snow Leopard and lion, but now gets a "sticky" pointer within a few hours.  If I reboot, the problem goes away for a few hours. Similarly, if I unplug the mouse and plug it back in the problem seems to go away for a time.
I found a few other references to this problem, but I have yet to see a solution.  Has anyone found a solution that I simply have come across yet?

Answer 1

EDIT:
ACTUAL FIX, AND YOU'RE NOT GONNA LIKE IT!
I've found that I only ever experienced mouse lag, when my RAM (memory) usage peaked, resulting in Windows being forced to do disk paging to cope with my lack of RAM.
You can see if this is your problem, by hitting CTRL-SHIFT-ESC to open the Task Manager, and go to the Performance tab (do this just after a fresh reboot!!! See why below.). Leave it open, and try doing a lot of things at once (open a browser with many start-up
tabs while opening some RAM-heavy program, like a programming IDE or a video editing suite). If it peaks, and your mouse subsequently lags, you probably need more RAM for your purposes.
This also explains why people can be posting so many different false "fixes". Whenever the lag occurs, because some operation needs more RAM, the data is cached
in the page file. So when people have experienced lag while using their computer, and then do something to try and fix their problem, and try the same things that made the computer lag before, all those things are already cached, and therefore won't lag anymore...until
you restart your computer, or the pagefile has been filled with new data.
The fix for me, ended up being installing more RAM. If you do not have that option, try to limit the number of programs simultaneously running on your computer. One way
to do this, is by unchecking unneeded start up programs, using these steps:
1. Start ==> Run
2. Type in: msconfig
3. Hit enter the Startup tab
4. Untick all programs THAT YOU KNOW, which you do not need to have available at start up.
Another way, is to remember to close programs when you're done with them.