'iTunes.smi file missing'. Can't open iTunes

I got a seriously problem to open iTunes grogram on my PC.
'iTunes.smi file missing' or 'can't located' prompted  when I intented to repair, uninstall or reinstall. I'd tried to seek this file in my local C driver and My Network Space. but un success. So I can’t open my iTunes in any way.
A captured screen attached below when I tried to repair
A captured screen attached below when I tried download from Apple web and install iTunes .

What follows is a LOG that I took as I dealt with the above problem noted in this post. I apologize for the *CAPS LOCK SYNDROME* and the *AKWARD NATURE OF MY PROCESS* but *IT WORKED!!!*
*IWEB REDESIGN PROBLEM (April 13, 2008)*
1. OPEN DOMAIN FILE AND RENAMED 'index-new.xml' to 'index.xml'
2. STILL NO CHANGE AND CANNOT OPEN IWEB FILE!
3. AFTER SOME TIME IT OPENED THE FILE BUT COULDN'T FIND ALL MEDIA FILES (LINK SEEMED BROKEN)
4. COPIED BOTH DOMAIN AND DOMAIN.SITES FILE TO EXTERNAL HD.
5. TRASHED REMAINING DOMAIN FILES FROM APPLICATION SUPPORT/ IWEB FOLDER.
6. TRANSFERED ORIGINAL DOMAIN FILE (SAVED) FROM EXTERNAL HD TO INTERNAL HD IWEB FOLDER.
7. DELETED PLIST FILE FROM PREFERENCES.
8. OPENED IWEB APPLICATION WHICH CREATED NEW DOMAIN FILE (of course).
9. TRASHED NEW DOMAIN FILE.
10. TRIED TO OPEN ORIGINAL DOMAIN FILE WHICH I RENAMED AS 'Domain (redesign 2008)' BUT IT WOULDN'T! STARTING FROM NEW DOMAIN FILE INSTEAD!
11. TRIED TO RENAME THE ORIGINAL FILE BACK TO JUST 'DOMAIN' AND WALLAH AFTER MUCH TRIAL AND ERROR ORIGINAL FILE IS BACK EXACTLY AS I LEFT IT BEFORE UPLOADING TO .MAC ACCOUNT LAST NIGHT.
THOUGHTS:
Something definitely happened to the original domain file when it was being uploaded to .mac account and the renaming of the index.xml file to index-new.xml plus the inclusion of another 'Domain.sites' file in my iWeb folder where originally there was only one 'Domain' file caused the confusion and resulting panic that followed! AAAAAAAAAAAAAAAAAH!
The crazy thing is that this will probably happen again as I make more changes (redesign) and upload them to the mac server. If someone has a *REAL FIX* to prevent this CHANGE from happening - *PLEASE POST THIS HERE!*
Good luck to all who read this and remember: 'When there is a will, there is a way!'

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