Itunes will not open and I get the following error window

the folder itunes is on a locked disc or you do not have write permissions for this folder
powermac running Lion OS
uninstalled itunes, verifyed premissions. repaired disc
macbook the same thing happens

Thanks BDAqua, now I just need to get Itunes straightened out on my Macbook. I downloaded latest version and it crashes upon start.

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