Keynote stops working when I try to open a document

Dear all,
I finished a very important presentation today and saved it as keynote doc, and export it as ppt document so I could use it with the PC.
Now I am trying to open same document in Keynote and the whole mac becomes EXTREMELY SLOW and freezes. I have Mac Office 08 also and I have just tired to open ppt version of same document in Microsoft Powerpoint. Same result: mac becomes extremely slow and opening of 15MB document seems like eternity.
What's wrong?? What to do?

Constantin,
Thank you for your response.  I've attached screnshots showing the version details for kernal32.dll and ntdll.dll.  I also looked at the updates to see which might have been installed when the problem started.  Unfortunately there are 15-20 updates every month.  I didn't take note of when the error started to occur.  At first it only affected my ability to open files from within the project (i.e. file->open->Source, etc).  Then I went back to modify a project that had a SelectFilePopup and found that that wouldn't work either. 
Attachments:
ntdll.dll version.jpg ‏15 KB

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