Lightroom crashes at start up with the error message "Lightroom encountered an error when reading from its preview cache and needs to quit".  Please advise on how to fix this error.  Thanks

Lightroom crashes at start up with the error message "Lightroom encountered an error when reading from its preview cache and needs to quit".  Please advise on how to fix this error.  Thanks

You probably need to delete your preview cache.  See here  
Why And How To Clear Your Lightroom Cache - Lightroom Fanatic
Preference and other file locations in Lightroom 5

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