Macbook pro system running slow - etrecheck shows issues - any idea how to apply fixes?

Question

Hi I normally consider myself pretty web savvy but I'm totally lost on what to do here. This computer has been running slow since I got it, but the harddrive went sideways recently. I've never worked with a recovered drive - which I apparently have as my terminal lists my workfolder-2 so....I'm guessing I'm pretty screwed. I learned about etrecheck through the forums here but don't understand how to apply it
Would anyone help me understand what I need to do?
Here's my etrecheck:
Problem description:
very slow osx system even with only one or two apps open - standard 2013 macbook pro
EtreCheck version: 2.1.5 (108)
Report generated January 1, 2015 9:52:46 PM EST
Click the [Support] links for help with non-Apple products.
Click the [Details] links for more information about that line.
Click the [Adware] links for help removing adware.
Hardware Information: ℹ️
  MacBook Pro (13-inch, Mid 2012) (Verified)
  MacBook Pro - model: MacBookPro9,2
  1 2.5 GHz Intel Core i5 CPU: 2-core
  4 GB RAM
  BANK 0/DIMM0
  2 GB DDR3 1600 MHz ok
  BANK 1/DIMM0
  2 GB DDR3 1600 MHz ok
  Bluetooth: Good - Handoff/Airdrop2 supported
  Wireless:  en1: 802.11 a/b/g/n
Video Information: ℹ️
  Intel HD Graphics 4000 - VRAM: 512 MB
  Color LCD 1280 x 800
System Software: ℹ️
  OS X 10.8.5 (12F45) - Uptime: 4 days 8:16:35
Disk Information: ℹ️
  APPLE HDD HTS545050A7E362 disk0 : (500.11 GB)
  disk0s1 (disk0s1) <not mounted> : 210 MB
  Macintosh HD (disk0s2) / : 499.25 GB (310.25 GB free)
  Recovery HD (disk0s3) <not mounted>  [Recovery]: 650 MB
  HL-DT-ST DVDRW  GS31N disk1 : (369.9 MB)
  disk1s1 (disk1s1) <not mounted> : 54 MB
  disk1s2 (disk1s2) <not mounted> : 26 MB
  disk1s3 (disk1s3) <not mounted> : 34 MB
  disk1s4 (disk1s4) <not mounted> : 33 MB
  disk1s5 (disk1s5) <not mounted> : 65 MB
  disk1s6 (disk1s6) <not mounted> : 29 MB
  disk1s7 (disk1s7) <not mounted> : 26 MB
  disk1s8 (disk1s8) <not mounted> : 20 MB
  disk1s9 (disk1s9) <not mounted> : 36 MB
  disk1s10 (disk1s10) <not mounted> : 12 MB
  disk1s11 (disk1s11) <not mounted> : 35 MB
USB Information: ℹ️
  Apple Inc. FaceTime HD Camera (Built-in)
  Apple Inc. Apple Internal Keyboard / Trackpad
  Apple Inc. BRCM20702 Hub
  Apple Inc. Bluetooth USB Host Controller
  Apple Computer, Inc. IR Receiver
Thunderbolt Information: ℹ️
  Apple Inc. thunderbolt_bus
Configuration files: ℹ️
  /etc/hosts - Count: 2
Gatekeeper: ℹ️
  Mac App Store and identified developers
Kernel Extensions: ℹ️
  /Applications/VMware Fusion.app
  [not loaded] com.vmware.kext.vmci (90.4.18) [Support]
  [not loaded] com.vmware.kext.vmioplug.10.1.24 (10.1.24) [Support]
  [not loaded] com.vmware.kext.vmnet (0104.03.86) [Support]
  [not loaded] com.vmware.kext.vmx86 (0104.03.86) [Support]
  [not loaded] com.vmware.kext.vsockets (90.4.23) [Support]
  /System/Library/Extensions
  [loaded] at.obdev.nke.LittleSnitch (4228 - SDK 10.8) [Support]
  [loaded] com.globaldelight.driver.BoomDevice (1.1 - SDK 10.1) [Support]
  [not loaded] com.waltop.iokit.driver.USBAtTablet (1.1.0) [Support]
Problem System Launch Agents: ℹ️
  [failed] com.apple.accountsd.plist
  [failed] com.apple.CalendarAgent.plist
  [failed] com.apple.coreservices.appleid.authentication.plist
  [failed] com.apple.pbs.plist
  [failed] com.apple.printtool.agent.plist
  [failed] com.apple.tccd.plist
Problem System Launch Daemons: ℹ️
  [failed] com.apple.wdhelper.plist
Launch Agents: ℹ️
  [running] at.obdev.LittleSnitchUIAgent.plist [Support]
  [not loaded] com.adobe.AAM.Updater-1.0.plist [Support]
  [loaded] com.google.keystone.agent.plist [Support]
  [running] com.penpad.penpadtablet.plist [Support]
  [loaded] org.chromium.chromoting.plist [Support]
Launch Daemons: ℹ️
  [running] at.obdev.littlesnitchd.plist [Support]
  [loaded] com.adobe.fpsaud.plist [Support]
  [invalid?] com.adobe.SwitchBoard.plist [Support]
  [loaded] com.github.GitHub.GHInstallCLI.plist [Support]
  [loaded] com.google.keystone.daemon.plist [Support]
  [loaded] com.microsoft.office.licensing.helper.plist [Support]
User Launch Agents: ℹ️
  [loaded] com.adobe.AAM.Updater-1.0.plist [Support]
  [loaded] com.adobe.ARM.[...].plist [Support]
  [failed] homebrew.mxcl.postgresql.plist [Support]
User Login Items: ℹ️
  Boom Application (/Applications/Boom.app)
  iTunesHelper Application (/Applications/iTunes.app/Contents/MacOS/iTunesHelper.app)
Internet Plug-ins: ℹ️
  JavaAppletPlugin: Version: 14.9.0 - SDK 10.7 Check version
  o1dbrowserplugin: Version: 5.38.6.0 - SDK 10.8 [Support]
  AdobeExManDetect: Version: AdobeExManDetect 1.1.0.0 - SDK 10.7 [Support]
  Silverlight: Version: 5.1.20513.0 - SDK 10.6 [Support]
  FlashPlayer-10.6: Version: 15.0.0.246 - SDK 10.6 [Support]
  WidevineMediaOptimizer: Version: 6.0.0.12757 - SDK 10.7 [Support]
  QuickTime Plugin: Version: 7.7.1
  Flash Player: Version: 15.0.0.246 - SDK 10.6 Mismatch! Adobe recommends 16.0.0.235
  googletalkbrowserplugin: Version: 5.38.6.0 - SDK 10.8 [Support]
  AdobePDFViewer: Version: 10.1.1 [Support]
  Autodesk123D32: Version: Autodesk123D32 1.0.6 - SDK 10.7 [Support]
  DirectorShockwave: Version: 12.1.3r153 - SDK 10.6 [Support]
Safari Extensions: ℹ️
  Searchme [Installed] Adware! [Remove]
3rd Party Preference Panes: ℹ️
  remoting_host_prefpane  [Support]
  Flash Player  [Support]
Time Machine: ℹ️
  Time Machine not configured!
Top Processes by CPU: ℹ️
      3% coreaudiod
      2% Activity Monitor
      1% WindowServer
      1% activitymonitord
      1% Google Chrome
Top Processes by Memory: ℹ️
  168 MB Google Chrome
  49 MB Google Chrome Helper
  34 MB mds
  30 MB WindowServer
  26 MB Finder
Virtual Memory Information: ℹ️
  93 MB Free RAM
  1.39 GB Active RAM
  1.35 GB Inactive RAM
  1.45 GB Wired RAM
  48.43 GB Page-ins
  17.53 GB Page-outs

Answer 1

Searchme [Installed] Adware! [Remove]
Start by going to Safari/Preferences/Extensions and un-install the above.
17.53 GB Page-outs
Adding some RAM would help. Even though you haven't restarted for 4+ days, this is a little high. The 2 places I’ve seen recommended most to buy reliable RAM are below. I have purchased RAM several times from Other World Computing and have always been very satisfied with the product and service. They have on-line instructions on how to replace the RAM. OWC has also tested RAM above what Apple states is the maximum. I now have 6GB installed on a machine supposedly limited to 4 GB.
Crucial
Other World Computing
Activity Monitor – Monitor Performance Problems  
Performance Guide
Why is my computer slow
Why your Mac runs slower than it should
Slow Mac After Mavericks
Things you can do to resolve slowdowns  see post by Kappy