Outlook connection to exchange server problem

We have a new domain and an existing exchange server. The problem is if i log in with a local computer account i can autodiscover and connect in cached mode to exchange no problem. If i then login with a domain user account the same computer (tried on other
workstations) will fail to auto discover, fail to connect to exchange even with manual settings. I cant find anything obvious in Group policy.
The server is setup with the latest 2013 Group policy templates with office 2013 templates
Users not logged in with the new AD server can connect to exchange 
Users not logged into the domain can access exchange server
My feeling is its a local setting that is missing or needs to be changed in Group Policy but i am at a loss as to what it could be
I have disabled roaming profiles too and it makes no difference.
Any help would be greatly appreciated.
Steve

Hi,
Sorry for my delay. According to your description, I summarize your issue to the following points:
1. No problem when the user logs in Outlook with a local computer account in Cached mode.
2. Can’t connect to Exchange from an cache mode enabled Outlook 2013 client when using a domain user account on the same computer automatically or manually.
3. Can connect to Exchange from an online mode enabled Outlook 2013 client when using a domain user account on the same computer automatically or manually.
It is right? If I misunderstand, please feel free to point it out. Additionally, I noticed that the server is setup with the latest 2013 Group policy templates with office 2013 templates. Please confirm
if the Outlook cache mode is disabled by OTC or GPO. If there is following registry key applied on the machine:
Software\Microsoft\Office\15.0\Outlook\Cached Mode
Meanwhile, please try to install an Outlook 2013 with a fresh ISO file(Don’t use any template such as OCT template), see if the Cached mode Outlook can connect to Exchange server.
Waiting for your updates.
Regards,
Winnie Liang
TechNet Community Support

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