Photoshop CS4 Extended will not open file from Bridge.

Question

This is 2nd time this has occurred.  Last time I uninstalled CS4 and re-installed to fix it.  Prefer to not do that again.
System: XP Media center, SP3,  3 GB memory, Athlon 64x2.  Generic - motherboard graphic card.  18 GB disk space remaining.
Typical work flow is edit DNG files in Lightroom.  Once done, select DNG files in Bridge and under Tools run the Photoshop Image Processor which changes color profiles, sharpens and converts to JPEG and saves.  Done this probably a thoudand times.  Ran a batch Sunday afternoon fine.
I may have interrupted an Image Processor batch that was just starting and glitched something.
Now Bridge will open Photoshop but nothing gets imported with the Image Processor.  Also Bridge will not run a Batch.  Bridge will open Adobe Raw for editing a DNG but cannot load it into Photoshop.
Once I try any of these things, Photoshop will usually not close/exit and many menu items are shaded out.  For example, opening a file or starting a new file is not available.  Activate/Deactivate not accessible.  Can Deactivate and Activate through InDesign. Photoshop seems OK otherwise if re-started after re-boot.
Any ideas?
Thank you.

Answer 1

So far, no good.  Here is what I have done and current symptoms.
1) I backed up all the settings and workspace files, then deleted them.  No change.
2) No matter what I do, everytime I hold down the control, alt and delete keys when starting PS CS4 all I get is the Windows start settings "Adobe Photoshop CS4 Properties" box where you can select "Target" and "Start In" paths.  I do not get any dialog or confirmation to reset anything.
3) Bridge successfully reset preferences using the Control key while starting it up.
Everything about Bridge has appeared to function corectly before and after these changes.  But when the Tools/Image Processor or Batch is called, it starts Photoshop OK but nothing in imported to be processed.
Photoshop opens (either from import or stand alone start) with menus partially functioning.  Under the file tab, nothign important works.  Cannot open a file, cannnot start a file, cannot exit - all grayed out.  But keyboard shortcuts do work and I can open a file or start a new file using the shortcuts.  Once I get a file open with the keyboard shortcut, most of the menu functions come back under the file tab and can be used and can exit PS.  The "X" in the upper right corner to close the program still remains greyed out and not functional.  The Activate/Deactivate options under Help remain grayed out.
4) I deactivated the Suite from within InDesign and the I uninstalled only PS using the Windows uninstall utility.  I reinstalled PS from the CS4 Suite which of course reinstalled Bridge and some other utilities.  I reactivated from within InDesign and ran all updates from within InDesign since updates were still grayed out in PS. Encountered an error (Adobe CSI CS4 1.0.1,Adobe Drive CS4 1.0.1,Adobe Extension Manager CS4 2.1:Failed to install.)
Problems still exist as described.
5) Finally I deactivated again from within InDesign and re-installed the whole CS4 Suite without uninstalling anything before hand. I noticed that process did an uninstall before each module was re-installed.
Problems still exist as described above.  I did notice that Photoshop showed itself still Activated (but grayed out) in the help menu even though I had previously deactivated the suite before the re-install.  Ran complete Updates from within Bridge.  Encountered an error (Adobe CSI CS4 1.0.1,Adobe Drive CS4 1.0.1,Adobe Extension Manager CS4 2.1:Failed to install.) but continued on. Everything else updated OK.
I looked through the registry settings for the settings path as noted in referenced forum links and all looked correct.
Additional Notes:  I installed the OnOne Plugin Suite 4 a few weeks ago.  Everything has run smothly since then until this problem poped up.  After the Uninstall/reinstall the OnOne menu option appears as normal.  As do my old Nik plug ins.  I doubt this has anything to do with the issue.
Any more ideas outside of starting all over on a clean drive/machine which I really dread even contemplating?
Thank you.