Photoshop cs5 not working(opening) in vista (32bit)

i cannot access photoshop while accessing it from the start menu shortcut .it says adobe cs5 has stopped working.
But can access it through bridge without the filters.
please suggest a remidial solution.

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Are Photoshop and OS fully updated and have you performed the usual trouble-shooting routines (trashing prefs by keeping command-alt-shift/ctrl-alt-shift pressed while starting Photoshop after making sure all customized presets like Actions, Patterns, Brushes etc. have been saved and making a note of the Preferences you’ve changed, 3rd party plug-ins deactivation, system maintenance, cleaning caches, font validation, etc.)?

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