Photoshop CS5 will NOT open with Windows 8

I have photoshop loaded on an external hard drive. I was using Windows Vista, but that computer crashed. I purchased a new computer already loaded with Windows 8. Photoshop will not open. I do know there is nothing wrong with the version of Photoshop because if I take the external hard drive to a different computer, it'll open and work fine.
I have changed the compatibility to everything in the list, and nothing works to open Photoshop. I do not have the disk, so I can't uninstall/reinstall, but it's on an external hard drive to begin with.
Any ideas?

When you install on an external drive it writes files to the C drive on the computer you installed from.  PS will not work if you plug external into another computer as it does not have the licencing files on the other computer.   So in effect the external is only good for one computer.

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