Photoshop will not open = error message End of file unexpected issue

When I try to open PS it gives me the error message "Could Not iniitialize Photoshop due to an unexpected end of file issue"
I have rebooted, closed all the other programs,
Support is closed for the weekend.
Any suggestions would be appreciated!

I uninstalled and reinstalled and it still won't open either from the desktop icon or from within lightroom

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    T
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    Sr Product Manager, Font Solutions
    Extensis, a division of Celartem, Inc.

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