PR - material number gray out field

hello
I need to know if there is any way to gray out Material number field  in PR when I just enter to Tx Me51n.
thks in advance.

Dear,
This action need to be done in development Enviro.
go to IMG  screen -.> MMPuchasing---> Purchase Requisition --- > Screen Layout  , Choose ME51N (Screen Variant) field Material No choose Display.

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