Since upgrading to 3.6.15 and Adobe Reader X I can't open PDF files

If I try and open a PDF file get message saying problem with Adobe reader, if it is running exit and try again. However it is not running. I then get a blank screen. If I close FF next time I try to open it a message says FF is already running and I have to reboot to clear the problem. This happens on both my desktop running XP and my laptop running Vista but only since I upgraded to 3.6.15. I upgraded Adobe to Ver X a week ago and it worked fine until the latest FF update.
The problem doesn't happen in IE.

The same as all other Mac apps. Which is to say:
Open Finder.
Look in the left column for Applications.
Click to open.
Find Adobe Reader. Open a folder if needed.
Double click to launch Adobe Reader.

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