Some applications are not opening, including mail and Word.  Clicking on the icon stirs it on the dock, but will not open it.

Some applications are not opening, including Mail and Word.  Clicking on the icon stirs it on the dock, but will not open it.  Any suggestions?  Thank you!

Ok, that's plenty of space.
Check the S.M.A.R.T. status on your HD: Boot from install disc (insert disc > restart > immediately hold down the c key and keep holding it until you see “Preparing Installation”) > at first screen select the language and click Continue > click on the Utilities Menu in the menu bar > select Disk Utility > select your HD in the panel on the left side (the name of the HD’s manufacturer and the model number, usually the top item in the list) > look at the bottom of the main window next to S.M.A.R.T. status and see if it says “Verified” (good) or something more ominous like “Failing.”
If S.M.A.R.T. status is "Verified," run Repair Disk > click Repair Disk at bottom of main window. Run this at least twice, and keep running it until it says “appears ok” twice in a row. If that doesn’t happen, you may need a stronger utility (such as DriveGenius, TechToolPro, DiskWarrior) or if the directory is damaged beyond repair, you may need to reinstall the OS, or you may have a damaged HD which will need to be replaced (repair utilities can only repair the directory structure, not the HD itself). When this is finished, quit Disk Utility, quit the installer, and restart. Once booted normally, go to Applications > Utilities > Disk Utility and run Repair Permissions.

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