Static Arp Entry for Exchange 2010

Hello All,
I was hoping someone could assist with an issue that our Exchange team are having, specifically with replication traffic traversing our DC to DR site.
The infrastructure consists of a Layer 3 data centre and a disaster recovery site, so essentially its a live/backup environment. Both the DC and DR site are connected with a LES using routed interfaces.
The Exchange cluster at the DC is associated with the following subnets:
MAPI - 10.1.30.X
Replication: 10.1.230.X
DR site has the following subnets associated with the exhange cluster :
MAPI - 192.168.4.X
Replication - 192.168.230.X
When an attempt is made to create a database/mailbox on an exchange server at the DC and copy it using  the replication subnet source: 10.1.230.X to destination subnet: 192.168.230.X, the copy process fails.
Replication traffic in general going from DC to DR or vice-versa is subject to constant problems and seems unreliable. Our exchange team have to manually copy mailboxes from one cluster to the other using Windows explorer which works fine.
The Exchange cluster at both sites reside within a VMWare ESX enclosure and connect to Cisco 6500 switches. Would the Cisco switches require a static arp entry for their respective Exchange clusters, which should be configured on each switch? If this was missing could this be the root cause of the replication problems we're experiencing? Or does this depend on whether the exchange cluster is using NLB Unicast or Multicast mode?
Any assistance would be most appreciated.
Regards,
Jamie

Jamie,
Have a look at this link:-
http://www.cisco.com/en/US/products/hw/switches/ps708/products_configuration_example09186a0080a07203.shtml
It depends on how the team NLB is set up.
You may need static mac & static arp as well as disabling igmp snooping if multicasting is bein used.
Regards,
Alex.
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