Unable to open PDF files after update failed

I have not be able to open any of my many PDF files after last update.  The update failed - error message "Error 1327.Invalid Drive:F\".  Drive F is where I plug in my flash drive, there is nothing in drive F.  I am working on my Ed.D and have 100's of PDF files pertaining to my research.  I need to be able to open these files.  I use a lot of these every day.  I can't unstall the program -- get the same error message, can't repair it.  Nothing works.  Can anyone tell me what to do.  I need a answer fast.

Some people in other posts have suggested to insert a USB drive into F drive.

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