Updated OS X Mavericks and now USB ports and MS Office apps won't work. How do I fix this?

I updated  my MacBook Pro (mid 2012) to OS X Mavericks 10.9.4 and now my USB ports and MS Office apps won't work.  What do I do to fix this?

What system version were you running before you updated to 10.9.4? Another 10.9.x or something earlier?
What version of Office? 2004, 2008, or 2011?
Were you aware that Office 2004 does not run on recent versions of the system?
When you say your USB ports do not work, on what are you determining that?
Were you aware that Mavericks does not display external disk volumes by default?

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