USB audio to USB audio

I have audio hardware that does audio I/O with the Mac through a USB connection.
I have another piece of hardware that does audio I/O with the Mac through a USB connection.
I would like to route the audio out from hardware A to audio in of hardware B, and vice versa. Do you know of an application that would enable this cross connection?

Quite possibly I have not described the challenge adequately.
Picture, if you will, an audio tape recorder and a sound system. The out port of the tape recorder is plugged into the in port of the sound system. The out port of the sound system is plugged into the in port of the tape recorder. I'd like to essentially replicate that. For example, suppose that my tape recorder is USB connected - I can play into the Mac, I can record from the Mac. I also have the headset (headphone & microphone combo). I want software that cross connects the two as described above. Once cross-connected, I can record my speech on the tape recorder, and hear the tape recorder play back through my headphones. Now replace the USB tape recorder with a USB-interfaced two-way radio. I speak into the mike, the audio is converted within the mike assembly, the encoded audio is passed into the Mac, transferred to the other USB port where the encoded audio is passed to the radio device, where it is restored to analogue and used to modulate the radio carrier. Similarly, what is heard by the radio is passed to the headphones of the headset.
The software that I am seeking would have the ability to deal with two separate USB inputs and two USB outputs. A mixer probably can deal with two or more discrete inputs, but probably not keep the two inputs isolated and passed to two outputs as required by the application.

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