When installing a new OS it does not recognize my HD as the start up disk

I am trying to upgrade from 10.6.8 to anything newer. When trying to install any of the newer OS when it prompts me to pick a HD and I pick my internal HD it says that this drive cannot start this computer. Therefore it will not allow me to install the OS. I have verified, repaired, repaired the permissions in the disk utility. I have verified that my internal HD is the start up disk. The computer starts up and

try booting into the Safe Mode using your normal account.  Disconnect all peripherals except those needed for the test. Shut down the computer and then power it back up after waiting 10 seconds. Immediately after hearing the startup chime, hold down the shift key and continue to hold it until the gray Apple icon and a progress bar appear. The boot up is significantly slower than normal. This will reset some caches, forces a directory check, and disables all startup and login items, among other things. When you reboot normally, the initial reboot may be slower than normal. If the system operates normally, there may be 3rd party applications which are causing a problem. Try deleting/disabling the third party applications after a restart by using the application un-installer. For each disable/delete, you will need to restart if you don't do them all at once.
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