Why do Hyperlinks clicked in Outlook cause General application error and do not open

When a hyperlink is selected inside an email in Outlook by clicking an error box opens "General Application Error" and it repeats the hyperlink address and says it is a general fault. This is a recent development as hyperlinks used to open a few days ago. Firefox V6 and Outlook V12, both updated today with no change on error.

Do you have that problem when running in the Firefox SafeMode?
[http://support.mozilla.com/en-US/kb/Safe+Mode]
''Don't select anything right now, just use "Continue in SafeMode."''
If not, see this:
[http://support.mozilla.com/en-US/kb/troubleshooting+extensions+and+themes]

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