Why does Adobe Reader Not work in either Firefox or IE?

Running Windows 7 Professional 32-bit.  Adobe Reader X (latest version just downloaded March 2012) works fine with files saved locally.  But whenever a website tries to open up a pdf file I keep getting the error message:
"There is a problem with Adobe Acrobat/Reader.
If it is running, please exit and try again.
(1074724867.3)"
I have tried numerous things posted on the web but I still keep getting the same error.

I have the same or a very similar issue on WIn7 64bit

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