Why would Dreamweaver CS5 become inaccessible on a Vista 64/SP2 system after install and reboot?

Question

Here's the scenario:
1) I install a purchased, valid Dreamweaver CS5 instance on a machine running Vista 64/SP2
2) The installation goes perfectly -- no errors or warnings whatever.  The proper startup menu items are created
3) I successfully launch Dreamweaver after install -- it works perfectly
4) I reboot
5) I try to re-launch DW
6) I get a bizzare system message saying 'Windows cannot access the specified device, path or file.'
Note that my virus checker is Avast, and I cannot see that it has touched any of the Dreamweaver files, and further note that every other of the dozens of applications i have installed have installed and run perfectly.
What the heck is going on with Adobe Dreamweaver (Which, by the way, installed perfectly on another machine using this exact, same OS image -- i upgraded my hardware a while back)

Answer 1

I'm surprised you've never experienced this with other software installations.  It's so typical of Windows' annoying UAC introduced in Vista. The first time you run software after reboot, you have to right click to run with admin level permission status so you can write to and save files on your HD which are necessary for the software to run on your system.   Afterwards, Windows remembers and usually permits you to start the software normally.
Nancy O.