Win7 Client got mouse lag with roaming profiles

Hello!
I got several clients, served by a Win2008r2 AD. Those clients supposed to have roaming profiles. Now if I enable them, there is a mouse lag, like the pointer is always in delay, also if you click, you notice that it takes longer than
normal.
If I logon with a local profile, none of that problem occurs.
No event logs
No change when use a fresh/new profile either
No rootkit/virus etc.
No overheating the hardware etc.
Does someone have an idea where I could look?
How I could diagnose a problem if I have GPO's interfering?
Thanks
Roger

Hi,
are your users potentially running multiple different OS versions?
Do you use custom mouse drivers on some of your hardware?
A possibility I see is mouse configuration information in the userprofile. if that information does not match what is expected, such issues can occur.
If the issue occurs, verify the mouse settings from control panel.
MCP/MCSA/MCTS/MCITP

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