10.5.6 Update screwed up my Finder/Dock (Macbook Pro)

I have a year old Macbook Pro and I just did the new update. It boots in and everything looks fine, but I can't click on any doc items, nor click on anything at the top "Finder, File Edit etc..". I can browse the HD and when I try to launch an app nothing happens.
What is going on??
Message was edited by: rvrabel

A random messaged popped up saying "You cannot open the application "(null)" because it may be damaged or incomplete.
Not sure if that is in reference to something I clicked to open?

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