10.6 -- All Office 2008 apps hang at splash screen. FontCache Tool runaway

Did an upgrade of 10.5 to 10.6. Nearly everything works fine. Can't launch Office 2008. All apps hang at their splash screen; usually at Optimizing Font Menu Performance.
Once an app is opened, in Activity viewer you'll find a process called FontCache Tool using >90% of the CPU (on my Core Duo MBP at least, YMMV). I suppose it's saying a lot about 10.6 that the computer is completely usable with that runaway process. Even after forcing the office app(s) to quit, Font Cache Tool stays running until it's killed manually.
I have yet to find out if FontCache Tool is an Apple or MS process. I think it's microsoft.
This happens under multiple users.
This happens after reinstalling Office.
This was an Office 2008 upgrade from Office 2004.
After reinstall, and installing Rosetta, office 2004 will run, but office 2008 will not.
Office 2008 is 12.2.1.
I am running FontAgent Pro for font management, and so font book sees certain activated fonts as duplicates. (Validate fonts shows duplicate warnings but no errors). FontAgent Pro 4.0.3 is listed as Snow Leopard compatible. So is Office 2008.
I have yet to do a clean SL install, which I'm guessing will fix it, but I'm curious if there is a sub-sledgehammer approach, or if I am the only person with this issue.
Other probably irrelevant facts include that the computer is bound to both Active Directory and OS X OpenDirectory servers. Open Directory is running on Leopard 10.5 Server. It does have some managed preferences, including those for Office (e.g. to set default to .doc rather than .docx) but the situation persists even after removing those managed preferences.
Normally really specific problems are easy to isolate and solve, but I'm at a loss.
Any help appreciated
keppie

Hey i think i figured it out.
Had the same prob. 10.6 12.2.1 entourage hanging.
Renamed FCT, instantly prompted that a font was corrupt. Removed the corrupt Font: KufiStandardGK.ttf << this just happened to be my one corrupt font.
A little troubleshooting i did leading up to this, I read your post and my situation was the same. I use Linotype X to manage fonts. I disabled all but the minimum fonts (i moved them into a folder font_trouble in the same folder)
I also deleted every office pref/plist setting i thought relevant to startup which triggered the microsoft setup assistant (watched via the console app) and it ran through its check and then immediately the fontcachetool started and went awol on cpu time. Once i killed it--during the starting up of word and entourage... timing may be unrelated but i did them at nearly the same time.
Ps. Your post was extremely well written and I apologize for my stream of consciousness, less than stelllar response... hope this helps if not feel free to ping me for more details on what I did...
Good Luck.. All my office apps are running normally now.

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