40GB Windows Directory - How to cleanup?

It seems our Citrix XenApp server 6.0 with Windows 2008 R2 x64 is running out of space on a 60GB system drive. I have quite a few other servers with the same size root drive and do much heavier lifting than this server with plenty of space available still.
After checking 4+ other servers the entire windows directory is under 20GB total on all of them. 
Using TreeSize I'm able to see that its my Windows folder alone is very close to 40GB. C:\Windows\Installers folder that has ramped up to 18GB itself!
I've used cleanmgr.exe but it doesn't find anything to cleanup!  After some research I found a few articles about this but nothing conclusive that I want to try on a production server. 
Obviously adding more disk space would be the quick/easy solution.  Something is telling me I would run into the same problem later and be wasting more time/space. How would you go about shrinking the size of the windows directory? 
Did a bit of looking for msizap.exe and it turns out that MS had decided not to include it in their installations anymore or via Windows Update.  I was able to get it from elsewhere though.  It ran, deleted 1 file, kicked a few errors (other sources
say the errors are fine and will still cleanup what it can).  
Ran DISM command and it came back with nothing.  (DISM.exe /online /Cleanup-Image /spsuperseded)
Still have a very large windows folder :( 
ps: I had images but it woulndn't let me upload D:

C:\Windows\Installed is Windows Installer cache which is used to store important files for applications installed using Windows Installer technology. The size of this folder depends of the installed applications and that is why you do not have the same with
other servers. This folder should not be touched as doing that would require rebuilding the OS and reinstalling the applications as mentioned here: https://support.microsoft.com/kb/2667628?wa=wsignin1.0
The folder size should not increase as long as you have not installed new applications. So, if you are running out space, I would recommend increasing the size of the C drive.
This posting is provided AS IS with no warranties or guarantees , and confers no rights.
Ahmed MALEK
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