64 Bit CS5 Won't run after I unchecked the 'C' Scratch Drive....

The problem started when I went into the 64 bit version of CS5;  edit : preferences : performance and in the scratch drive options I unchecked the ‘C’ drive option. (I know.... doesn't make sense to do that)  CS5 runs from the C drive BTW.  I then closed the program and on restart it would not work. When trying to open CS5 64 bit version I get an Adobe Photoshop CS5 message that states: “Could not open a scratch file because the file is locked or you do not have the necessary access privleges.  Use the ‘Properties’ command in the Windows Explorer to unlock the file. When I click on the OK button I get a second message that says, “Could not initialize Photoshop because the file is locked or you do not have the necessary access privledges.  Use the ‘Properties’ command in the Windows Explorer to unlock the file. Un install and install takes me to the same problem.  For what it’s worth the 32 bit version of CS5 runs fine. This is probably an easy fix for an expert but alas... that is not me. Any suggestions would be appreciated. Thanks in advance. Richard on the Eastern Shore of Virginia

The root cause is likely a permissions issue.  You need to make sure you have Full Control privileges to the root folder of each of the hard drives you have told Photoshop to use, as well as to the folder identified on your system by the TEMP environment variable.
Also, you may want to just turn off Windows UAC entirely, though you should research UAC and fully understand what it does and what the additional risks are before making the decision to do this.
A quick fix for you to get you working again might be to press and hold the Control and Alt keys immediately after starting Photoshop from its icon or menu item.  If you're quick enough, it will pop up a dialog allowing you to re-specify the scratch disks you had before when it worked.
-Noel

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