Access denied error when saving (but saves document regardless)

We have been getting a rather strange issue for a quite a long time with saving Microsoft Office documents. I suppose I should start with a rough background to our environment. I work for a multi-national company, that uses a mix of Windows 7 and XP machines
running Citrix Xenapp to connect to a central Citrix hub, spread over several smaller individual servers, all running Windows server 2012, with a centralized file server for the company. The issue is only occurring in the UK offices (to my knowledge, and so
far that I've seen only on the Windows 7 machines.
the error message itself, which is "The operation has been cancelled due to restrictions on this computer. Please contact your system administrator." which in normal circumstances, we would put down to permissions for the file. However, no matter
the access granted to the file, be it full control and creator owner, this error will always appear. Once the message is closed, the file will save as normal, as if there was no issue.
It only seems to be happening for a handful of users, on completely different servers. What makes this stranger is that it cannot be put down to a Citrix profile issue, or a software installation issue with Microsoft office, as other users on the same server
as those who have this issue, encounter no problems at all, and a complete deletion of their citrix profile fails to fix it either.
Does anyone have any idea what could be causing this problem? Any help or indication of where to begin looking would be greatly appreciated!
Regards,
Rich

Hi,
For your circumstance, I'd like to suggest you use Process Monitor to caputer system activity.
Process Monitor:
http://technet.microsoft.com/en-us/sysinternals/bb896645.aspx
Note: use process monitor during save office document. After that, check its records.
Roger Lu
TechNet Community Support

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