Acrobat (and InDesign) performance issues after virus

Hi everyone,
we have a problem with our system (spec listed below);
System
Dell Precision T7400
CPU(s): dual quad core Xeons
RAM: originally 2GB, upgraded to 4GB 1 day ago
OS: XP 32-bit
Adobe Software: Originally CS3 Suite, now CS5 Suite
                         Acrobat 9 Pro
Problem
Acrobat: 1. stutters slowly when scrolling, almost crashes
             2. Takes 4X longer than before to "Reduce file size" for PDFs
InDesign: stutters slowly when working with text, almost crashes
Cause
Virus infultrated system about 1 month ago.
Attempts
1. Re-imaged disc and installed software based mirroring software with 2 extra backup drives: system still lags
2. Re-formatted, reinstalled: system still lags
3. Turned off mirroring: helped a little
4. Ran various memory, motherboard tests: nothing found
5. varified all BIOS and firmware up to date
6. Uninstalled mirroring software, installed hardware based mirroring software, reformatted, reinstalled: system still lags
7. Tried working with files directly from C:/ with no mirroring: system still lags
8. Installed fresh 4GB memory: system still lags
9. Have tried all methods of helping InDesigns performance but no luck.
Thoughts
Comparing this system to my old laptop (Centrino Dual Core), the laptop runs about 4X faster since the virus. Before the virus, this system was a dream to work with, super fast speed, never lagged.
I keep thinking that the virus must have damaged somthing on the motherboard, but error messages or motherboard beep codes.
Any other suggestions (short of shotting this system) would be greatly appreciated.

Are you sure it only happens with Acrobat and ID, it could be a faltering hard drive
As far as I can tell. Photolop and Illustrator work fine, haven't had time to try the rest of the CS5 Suite apps.
I've ran tests on the C drive (10k rpm) and the added 1TB drives. Same results for all; lag lag lag.

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              [not loaded] com.cisco.nke.ipsec (2.0.1) Support
              [not loaded] com.leapfrog.codeless.kext (2) Support
              [not loaded] com.leapfrog.driver.LfConnectDriver (1.8.1 - SDK 10.7) Support
              [not loaded] com.rim.driver.BlackBerryUSBDriverInt (0.0.39) Support
              [not loaded] com.rim.driver.BlackBerryUSBDriverVSP (0.0.39) Support
              [not loaded] net.kromtech.kext.AVKauth (2.3.6 - SDK 10.8) Support
              [not loaded] net.kromtech.kext.Firewall (2.3.6 - SDK 10.8) Support
    Startup Items:
              CiscoVPN: Path: /System/Library/StartupItems/CiscoVPN
    Problem System Launch Daemons:
              [failed] com.apple.wdhelper.plist
    Launch Daemons:
              [loaded] com.adobe.fpsaud.plist Support
              [loaded] com.adobe.SwitchBoard.plist Support
              [running] com.fitbit.galileod.plist Support
              [loaded] com.google.keystone.daemon.plist Support
              [loaded] com.leapfrog.connect.shell.plist Support
              [loaded] com.microsoft.office.licensing.helper.plist Support
              [loaded] com.timesoftware.timemachineeditor.backupd-auto.plist Support
              [running] com.zeobit.MacKeeper.AntiVirus.plist Support
              [running] com.zeobit.MacKeeper.plugin.AntiTheft.daemon.plist Support
    Launch Agents:
              [not loaded] com.adobe.AAM.Updater-1.0.plist Support
              [loaded] com.adobe.CS5ServiceManager.plist Support
              [running] com.brother.LOGINserver.plist Support
              [running] com.google.keystone.agent.plist Support
    User Launch Agents:
              [loaded] com.adobe.ARM.[...].plist Support
              [failed] [email protected]
              [loaded] com.macpaw.CleanMyMac.helperTool.plist Support
              [running] com.microsoft.LaunchAgent.SyncServicesAgent.plist Support
              [running] com.zeobit.MacKeeper.Helper.plist Support
    User Login Items:
              Google Chrome
    Internet Plug-ins:
              o1dbrowserplugin: Version: 5.3.1.18536 Support
              Google Earth Web Plug-in: Version: 7.1 Support
              Default Browser: Version: 537 - SDK 10.9
              Flip4Mac WMV Plugin: Version: 2.3.8.1 Support
              OfficeLiveBrowserPlugin: Version: 12.2.9 Support
              AdobePDFViewerNPAPI: Version: 10.1.9 Support
              FlashPlayer-10.6: Version: 13.0.0.201 - SDK 10.6 Support
              DivXBrowserPlugin: Version: 2.0 Support
              Silverlight: Version: 5.1.10411.0 - SDK 10.6 Support
              Flash Player: Version: 13.0.0.201 - SDK 10.6 Outdated! Update
              iPhotoPhotocast: Version: 7.0
              googletalkbrowserplugin: Version: 5.3.1.18536 Support
              QuickTime Plugin: Version: 7.7.3
              AdobePDFViewer: Version: 10.1.9 Support
              GarminGpsControl: Version: 2.6.4.0 Release Support
              SharePointBrowserPlugin: Version: 14.3.9 - SDK 10.6 Support
              JavaAppletPlugin: Version: 14.9.0 - SDK 10.7 Check version
    Safari Extensions:
              Dashlane: Version: 2.4.0.55923
    Audio Plug-ins:
              BluetoothAudioPlugIn: Version: 1.0 - SDK 10.9
              AirPlay: Version: 2.0 - SDK 10.9
              AppleAVBAudio: Version: 203.2 - SDK 10.9
              iSightAudio: Version: 7.7.3 - SDK 10.9
    iTunes Plug-ins:
              Quartz Composer Visualizer: Version: 1.4 - SDK 10.9
    User Internet Plug-ins:
              Dashlane: Version: Dashlane 1.0.0 - SDK 10.7 Support
              Move_Media_Player: Version: npmnqmp 071705000010 Support
              WebEx64: Version: 1.0 - SDK 10.6 Support
              Picasa: Version: 1.0 Support
    3rd Party Preference Panes:
              Flash Player  Support
              Flip4Mac WMV  Support
              Growl  Support
    Time Machine:
              Skip System Files: NO
              Auto backup: NO - Auto backup turned off
              Time Machine not configured!
    Top Processes by CPU:
                   3%          WindowServer
                   2%          SystemUIServer
                   1%          diskimages-helper
                   1%          mds
                   0%          Google Chrome Helper EH
    Top Processes by Memory:
              94 MB          Google Chrome
              59 MB          GoogleSoftwareUpdateDaemon
              57 MB          Google Chrome Helper EH
              52 MB          Google Chrome Helper
              39 MB          Finder
    Virtual Memory Information:
              40 MB          Free RAM
              499 MB          Active RAM
              481 MB          Inactive RAM
              465 MB          Wired RAM
              7.33 GB          Page-ins
              502 MB          Page-outs

    The performance issues are due to third party software. Mavericks at the minimum requires 2GB's of RAM but I don't think that's the issue. And you can upgrade RAM anytime.
    MacKeeper should be uninstalled. It does far more harm than good.
    Do not install MacKeeper: Apple Support Communities
    Uninstall instructions > how to uninstall MacKeeper
    249.2 GB (67.82 GB free)
    Keep an eye on available disk space.
    Click your Apple menu icon top left in your screen. From the drop down menu click About This Mac > More Info > Storage
    Make sure there's at least 15% free disk space. Less can slow your Mac down.
    You also need to uninstall CleanMyMac >  How To Uninstall CleanMyMac
    Third party so called Mac cleaning utilities are not necessary on a Mac. Your Mac runs maintenance in the background for you.
    Mac OS X: About background maintenance tasks

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