Acrobat X Pro won't save document b/c it thinks a file is already open, but it isn't

I get an error message when I try to save a pdf. It says that it couldn't save the file because it is already open, but there's no other pdf file open.
What is causing Acrobat to think that more than one file is open when there is only one file open?

No, I'm running Windows XP.
The only thing open is Acrobat and the explorer window box that appears when you want to save a file.
It appears to me that Acrobat is still accessing data from a file that was previously open but is no longer open.
How do I make it so that Acrobat sees only the file(s) that are actually open and not files that have been closed?
My only way to work around this problem is to completely close Acrobat and then relaunch it in order to do what I need to do. Very inefficient.

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