Adobe Caslon Pro generates enormous PDF files on Mac Word, displays incorrectly on Word for Windows

Had a terrible experience trying to typeset my first document with Adobe Caslon Pro in Word. In Word Mac, 27 page all text document rendered to 70 MB PDF with Opentype features enabled, well under a megabyte with Opentype features disabled in compatibility settings for the same font. Opening same document in Word for Windows (both 2010 and 2013) displayed with incorrect (increased) line spacing and Opentype features (e.g. ligatures) disabled even though they were enabled in compatibility setting (they showed up when I opened the same document in Mac).

Something definitely doesn't sound right here.
We are not aware of any problems using Adobe Caslon Pro with Microsoft Word 2011 on the Macintosh.
Attached is a sample Word document that I created using Word 2011 (with all latest updates from Microsoft), four styles of Adobe Caslon Pro with all OpenType features enabled.
I created a PDF file using “save as PDF” from Word's own “save” dialog, also attached.
I also created a PDF file from the “print” dialog using the “save as Adobe PDF” function (lower left corner of the dialog box), also attached.
In terms of functionality, I don't see the problems you are experiencing. The only difference between the generic PDF and the Adobe PDF appear to be optimization of the fonts embedded in the PDF files.
In terms of cross-platform compatibility, with Microsoft Word, Excel, and Powerpoint, forget about it. Font handling is problematic when you go beyond simple typography and fonts that have only four faces - regular, italic, bold, and bold italic. The cross-platform compatibility problems really have nothing to do with Adobe fonts themselves.
          - Dov

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                        MessageBox.Show("PDF Generated Successfully");
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    Runtime Gridview content:
    Generated PDF File:
    Thanks & Regards RAJENDRAN M
    Hello,
    Since this issue is mainly related to iTextSharp which belongs to third-party, I would recommend you consider posting this issue on its support website to get help.
    Maybe the following forum will help.
    http://support.itextpdf.com/forum/26
    Regards,
    Carl
    We are trying to better understand customer views on social support experience, so your participation in this interview project would be greatly appreciated if you have time. Thanks for helping make community forums a great place.
    Click
    HERE to participate the survey.

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