Adobe Lightroom2 won't launch properly

I've recently installed Adobe Lightroom2 on my G4PB and it's having problems. When I try to open the app I get an error message "An error occurred when attempting to change modules" and this comes up after the (empty) Lightroom window opens - an empty central window, no side panels and though the modules appear on the upper right clicking on any just produces that same error message.
What I've tried so far:
Repairing permissions and verifying disk (which was ok - no problems found).
Trashing pref files for both Lightroom1 and 2.
Logging in with shift key - no login items
None of this worked.
Logging in as another user in a clean troubleshooting account - and this works! Normal Lightroom and no error message.
So it seems to be some conflict in my User folder, but I haven't a clue what. Lightroom1 had no problems previously. What has changed since is I've installed the latest Apple Security Update, but that would be system wide so if the app works when logging into another account, it can't be that.
Is anybody else seeing this issue? Any suggestions what to try next?
thanks,
ncm

I reinstalled Lightroom2 after trashing everything associated with it including the package receipt. Before installing I rebooted and logged in with shift key - no login items loaded - ran Repair Permissions and Verify Disk and all was well. Still get the same error message. Then quit and tried relaunching with option key and made a new catalog. No difference. Then opened Console and it had a log of the preceedings. See if anything makes any sense to you:
AHS[316] ahs_main()
AHS[316] patches loaded
DiskImageMounter[316]: [WSX:SUIS[244]] error loading prefs - creating defaults one
AHS[324] ahs_main()
AHS[324] patches loaded
DiskImages UI Ag[324]: [WSX:SUIS[244]] error loading prefs - creating defaults one
AHS[332] ahs_main()
AHS[332] patches loaded
Installer[332]: [WSX:SUIS[244]] error loading prefs - creating defaults one
AHS[349] ahs_main()
AHS[349] patches loaded
2008-08-03 20:00:57.795 Adobe Lightroom 2[349] Launch Services updated for UTI dyn.ah62d4rv4ge8026xdqf4a: was 'com.adobe.lightroom2', and is now 'com.adobe.lightroom2' result:0
Adobe Lightroom [349]: [WSX:SUIS[244]] error loading prefs - creating defaults one
AHS[352] ahs_main()
AHS[352] patches loaded
Image Capture Ex[352]: [WSX:SUIS[244]] error loading prefs - creating defaults one
2008-08-03 20:02:59.711 Adobe Lightroom 2[349] Failed to restore first responder
2008-08-03 20:03:03.384 Adobe Lightroom 2[349] Failed to restore first responder
2008-08-03 20:03:03.502 Adobe Lightroom 2[349] Failed to restore first responder
2008-08-03 20:03:03.618 Adobe Lightroom 2[349] Failed to restore first responder
2008-08-03 20:03:03.736 Adobe Lightroom 2[349] Failed to restore first responder
2008-08-03 20:03:03.938 Adobe Lightroom 2[349] Failed to restore first responder
2008-08-03 20:03:04.089 Adobe Lightroom 2[349] Failed to restore first responder
2008-08-03 20:03:04.425 Adobe Lightroom 2[349] Failed to restore first responder
AHS[356] ahs_main()
AHS[356] patches loaded
Adobe Lightroom [356]: [WSX:SUIS[244]] error loading prefs - creating defaults one
AHS[359] ahs_main()
AHS[359] patches loaded
Image Capture Ex[359]: [WSX:SUIS[244]] error loading prefs - creating defaults one
2008-08-03 20:04:00.203 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:02.443 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:02.698 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:03.438 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:05.063 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:05.423 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:05.540 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:05.657 Adobe Lightroom 2[356] Failed to restore first responder
2008-08-03 20:04:05.825 Adobe Lightroom 2[356] Failed to restore first responder
AHS[362] ahs_main()
AHS[362] patches loaded
Console[362]: [WSX:SUIS[244]] error loading prefs - creating defaults one

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