Adobe Photoshop CS3 had encountered a problem V10.0.0.0

Photoshop V10.0.0 will not open. It crashes as its loading the Twain drivers at start up. I am running Windows XP.
I've tried deleting the preferences file, reloading Photoshop and, as a desperate measure, deleting and reloading CS3. Nothing has worked. I tried upgrading photoshop but still no luck. Set my default printer to PDF, still nothing. Disabled my firewall, still nothing.....
The worst bit is its been working quite happily since June 07 and then in late Nov early Dec it decided not to work. I also had a printer problem during this time and reinstalled the printer software, but photoshop wasn't working before I did that.
The error I get is:
Adobe Photoshop CS3 has encountered a problem and needs to close
Error signature App Name: photoshop.exe
AppVer 10.0.0.0
ModName: unknown
ModVer: 0.0.0.0 Offset 0.0.0.0.0.0.0.4
Any assistance would be great - I am getting desperate!
Regards
Sally

When I uninstalled my Dell 944 printer Photoshop worked. When I reloaded my printer it crashed again. It seems to crash everytime it loads the TWAIN part of the photoshop opening screen.
I've tried downloading and installing the latest driver from Dell for the printer but its 2005 and the same as the one I have so no luck there.
I still need my printer to work (its my scanner as well) but I am desperate to get Photoshop back! Any clues??

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