Adobe Reader 10.1.1 will not open .pdfs

Adobe was working just fine when I was using it earlier this morning until I logged off to let another employee briefly use my computer. Since then I keep receiving an error message that says "Adobe Reader has encountered a problem and needs to close. We are sorry for the inconvenience." I uninstalled and then re-installed Adobe but I still receive the same error message. How can I fix this problem?

Adobe has a recent(2012-01-09)KB article http://kb2.adobe.com/cps/860/cpsid_86063.html entitled "Protected Mode troubleshooting". There is a similar article (2011-09-12) http://kb2.adobe.com/cps/901/cpsid_90161.html entitled Protected View troubleshooting.
I have had issues with Adobe Reader X hanging (not responding) due to a conflict between an antivirus program and the Adobe Reader X Protected Mode/Protected Viewer sandbox features.
khwajakhurram replied to my query suggesting unchecking the default Adobe Reader X Preferences >3D & Multimedia> "Enable hardware rendering for legacy video cards" setting and this solves the issues!
What is surprising is that Adobe Reader X's 3D & Multimedia settings report that the alternative preferred renderer modes are either software or DirectX9 .....on a Vista machine with DirectX11.
The video card on this machine is definitely not legacy but a recent quality Nvidia produced card. That is also the case on the other machines with the issue I have reported.
I went a step further and I have found that performance is vastly improved by changing from the default preferred renderer mode of DirectX9 to the alternative Software setting.
http://kb2.adobe.com/cps/860/cpsid_86063.html mentions that "certain configurations of anti-virus software that have not yet white-listed AcroRd32.exe" are "Unsupported configurations for Reader running in Protected Mode". Therefore I have also excluded AcroRd32.exe from virus scanning.
I am now able to use both Adobe Reader X's Protected Mode and Advanced Security without issue and performance is vastly improved. I am certain that your issues will also be solved.
notafan777, on another thread, suggested that theses problems are due to a legacy of sloppy code and this certainly seems to be the case here with these very odd default settings influencing performance to such an extent.

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Ideas?

Can you please send process monitor logs:
To take process monitor log follow the below steps:
1) Download process monitor from http://technet.microsoft.com/en-in/sysinternals/bb896645.aspx
2) Launch process monitor.
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I am able to open PDF in IE9 on win 7 64 bit machine using Reader 10.1
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Message was edited by: broken twig

You can try using this tool to first remove all traces of Reader from your computer:
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Can you please send process monitor logs:
To take process monitor log follow the below steps:
1) Download process monitor from http://technet.microsoft.com/en-in/sysinternals/bb896645.aspx
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3) Now try to open the PDF file at network share. It will not open with the network error so just cancel the error dialog.
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2. I deleted any acr*.tmp anywhere on my computer.
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4. I deleted the 6.0 folder from my install path.
5. I deleted the Adobe folder from my temp directory.
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7. I rebooted and repeated step 6.
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Adobe Reader will not open PDF in browser simple answer.

I just had this problem and was able to work through it with the help of tech support from TD Ameritrade. The fix is simple so read on. After uninstalling and reinstalling all things adobe and trying other recommendations on these forums I was stumped. I called my broker tech section since I couldn't open their reports and we identified what my specific problem was. For me, and I imagine some of you this will help and prevent a lot of wasted time.
Nothing was wrong with my Adobe Reader. My problem was that I have a 64 bit operating system and both of my default browsers were 64 bit browsers. I did not know my internet explorer default browser was the 64 bit one until the technician that assisted me informed me that a recent windows update made all 64 bit systems default to 64 bit internet explorer browsers. You cannot change that default by choosing between 64 bit and 32 bit, because you can only choose internet explorer. That explains why my attempts to open with a 32 bit browsers always failed. I also tried with Firefox thinking it was 32 bit and it failed as well. The technician informed me Firefox is a 64 bit browser and then it made sense. I guess the recent Adobe reader update caused a change that no longer allowed my 64 bit system and 64 bit browser to open PDF's through the browser. The technician who assisted me has a 64 bit system and only uses 64 bit browsers and can still open PDF's through those browsers. That confused us for a while until we realized he had his Adobe updater turned off and therefore had not been exposed yet to the update that originated my problems.
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My post was for those people who may not have realized yet that windows would not ever choose Internet expl. 32 bit over Internet expl. 64 bit if both exist on their system. For them it is easiest to just choose a default browser that only has a 32 bit version.
If I understood your reply correctly, you were telling me how to create a shortcut to Internet exp. 32 bit on my desk top. However, having that shortcut on my desk top and opening my browser through it will not prevent the problem of windows choosing my Internet exp. 64 bit browser for pdf's I try to open from the web. Thank you for your response, but I think the problem that I have tried to explain does exist for many users and can only be fixed by using a 32 bit browser that is not Internet explorer as your default browser. At some point if windows fixes the update that always chooses Internet expl. 64 bit over Internet expl. 32 bit, then this will all be irrelevant.
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From: kglad
To: ps walker
Sent: Monday, April 08, 2013 2:43 PM
Subject: Adobe Acrobat Reader x11.0.02 will not open
Re: Adobe Acrobat Reader x11.0.02 will not open
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