Adobe Reader 11.0.06 "There was an error opening this document.  Access Denied"

Windows 7 64-bit
If I go into My Windows 7 Documents Library folder (which is redirected by Group Policy to a network share), I get "There was an error opening this document.  Access Denied".  If I then map a drive to the share, I can open the PDF without the error message.
I've read a workaround for some time now for older versions has been to uncheck Enable Protected Mode at startup under Security (Enhanced) in Preferences.  I find this does work but this is probably not the best way to handle this situation.
I've also read one person removed the desktop.ini on the desktop to resolve.
Is there any official response from Adobe on this issue that I can be pointed too?  Are others still having this issue?
We plan to update several thousand clients and I'd like resolve this issue before we do.

We tried 11.0.05, 11.0.06 and 11.0.07 with the same result on different computers with different local Admin accounts.
When we re-install 10.1.0 the issue is gone and Protected Mode is enabled.
We then returned to 11.0.06 or 11.0.07
I'm logged in with a local Admin account.
I turned on Protected Mode Logging and captured what happens when I attempt to double click a pdf file in my Documents Library with 11.0.06 installed.  Access Denied.
I then doubled clicked the file from a drive mapped to the same share and the file opened.
[06:11/16:02:40] Adobe Reader Protected Mode Logging Initiated
[06:11/16:02:41] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:41] real path: \REGISTRY\MACHINE\Software\Adobe
[06:11/16:02:41] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:41] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:41] real path: \REGISTRY\MACHINE\SOFTWARE\Wow6432Node\Adobe
[06:11/16:02:41] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:41] NtCreateFile: STATUS_ACCESS_DENIED
[06:11/16:02:41] real path: \??\Volume{a758d00a-e81c-11e2-b856-806e6f6e6963}\$Extend\$Reparse:$R:$INDEX_ALLOCATION
[06:11/16:02:41] Consider modifying policy using these policy rules: FILES_ALLOW_ANY or FILES_ALLOW_DIR_ANY
[06:11/16:02:41] NtCreateFile: STATUS_ACCESS_DENIED
[06:11/16:02:41] real path: \??\UNC\nawrcs-bbc1fs\mousers\u212940\Documents\Citrix Adding a Printer.pdf
[06:11/16:02:41] Consider modifying policy using these policy rules: FILES_ALLOW_ANY or FILES_ALLOW_DIR_ANY
[06:11/16:02:41] NtCreateFile: STATUS_ACCESS_DENIED
[06:11/16:02:41] real path: \??\UNC\nawrcs-bbc1fs\mousers\u212940\Documents\Citrix Adding a Printer.pdf
[06:11/16:02:41] Consider modifying policy using these policy rules: FILES_ALLOW_ANY or FILES_ALLOW_DIR_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:46] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:46] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:46] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:47] NtCreateFile: STATUS_ACCESS_DENIED
[06:11/16:02:47] real path: \??\C:\Users\c702939\AppData\Local\Microsoft\Windows\Caches\cversions.1.db
[06:11/16:02:47] Consider modifying policy using these policy rules: FILES_ALLOW_ANY or FILES_ALLOW_DIR_ANY
[06:11/16:02:47] NtCreateFile: STATUS_ACCESS_DENIED
[06:11/16:02:47] real path: \??\C:\Users\c702939\AppData\Local\Microsoft\Windows\Caches\cversions.1.db
[06:11/16:02:47] Consider modifying policy using these policy rules: FILES_ALLOW_ANY or FILES_ALLOW_DIR_ANY
[06:11/16:02:47] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:47] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:47] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:47] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:47] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:47] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:47] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:47] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:47] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:47] NtCreateKey: STATUS_ACCESS_DENIED
[06:11/16:02:47] real path: \REGISTRY\USER\S-1-5-21-1691402968-2266345157-3523873211-67461\Software\Adobe\Adobe Acrobat
[06:11/16:02:47] Consider modifying policy using this policy rule: REG_ALLOW_ANY
[06:11/16:02:47] NtCreateFile: STATUS_ACCESS_DENIED
[06:11/16:02:47] real path: \??\C:\Users\c702939\Desktop\desktop.ini
[06:11/16:02:47] Consider modifying policy using these policy rules: FILES_ALLOW_ANY or FILES_ALLOW_DIR_ANY
[06:11/16:02:48] NtCreateFile: STATUS_ACCESS_DENIED
[06:11/16:02:48] real path: \??\C:\Users\c702939\Desktop\desktop.ini
[06:11/16:02:48] Consider modifying policy using these policy rules: FILES_ALLOW_ANY or FILES_ALLOW_DIR_ANY

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