Adobe Reader 11.0.10 will intermittently not open PDF files

On some user's computers Adobe Reader 11.0.10 will intermittently not open a PDF file. It will open fine 5 times in a row then maybe the 6th time it won't open. When it opens fine two AcroRd32.exe process start, when it does not open a single AcroRd32.exe process starts and will not go away unless you kill the process. The problem seems to go away if I turn off "Enable Protected Mode at startup" but I do not want to leave this disable.
Thanks!!

I don't have any inside information, but my experience over the last two years or so is that "Protected Mode" causes a plethora of different problems for (some) Windows users.  Disabling Protected Mode makes most of these problems disappear.
Occasionally Adobe staff recommends to re-enable Protected Mode, and on a few occasions this actually works.
The most baffling thing is that not all users experience any problems with Protected Mode; I myself have Protected Mode enabled on all Windows computers around me.

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