Adobe Reader 8.1 plugin error

I've uninstalled and reinstalled Adobe Reader 8.1 and have even run the patch for 8.1.2 and yet ever time I try to either open Adobe reader or a pdf file, I get an error message saying "Invalid plugin detected, Adobe reader needs to close" and I am unable to read any files at all.
I have Windows Vista and have recently installed Vista Service Pack 1, but the problem occurred both before and after Vista Service Pack 1 was installed. I've searched the forums and knowledgebase and have tried all the possible solutions that have been offered, but so-far nothing has worked.
Does anyone have any suggestions as to what I can do in order to resolve the problem? At this point Adobe Reader is completely unusable.
Thank you in advance for your help.
-Ron

I have the exact same problem running Vista. Has anyone offered a solution?
I uninstalled 8.1 and installed 7.1. It works fine, but I got a message warning of known Vista compatility issues

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